Research Associations

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Bias and causal associations in observational research.

Readers of medical literature need to consider two types of validity, internal and external. Internal validity means that the study measured what it set out to; external validity is the ability to generalise from the study to the reader's patients. With respect to internal validity, selection bias, information bias, and confounding are present to some degree in all observational research. Selec...

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Public sharing of research datasets: A pilot study of associations

The public sharing of primary research datasets potentially benefits the research community but is not yet common practice. In this pilot study, we analyzed whether data sharing frequency was associated with funder and publisher requirements, journal impact factor, or investigator experience and impact. Across 397 recent biomedical microarray studies, we found investigators were more likely to ...

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Nucleic Acids Research Subunit associations among chromatin particles

The self-association of oligonucleosomal chromatin particles in solution has been studied by light scattering and sedimentation. In the absence of magnesium ions no association is observed. In the presence of 70mM sodium or 2mM magnesium ions mono, di, tri and tetranucleosomes self-associate only if they contain bound histone 1. This association leads to the formation of compact aggregates and ...

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Advances in Dental Research on Behalf Of: International and American Associations for Dental Research O O

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ژورنال

عنوان ژورنال: Nature

سال: 1971

ISSN: 0028-0836,1476-4687

DOI: 10.1038/233433c0